Alprazolam

ATC: N05BA12
DDD: 1 mg oral
ICD-10: F41

Tmax (tablets): 1-2 h, Retard tablets 5 - 11 h
Half-life: 12-15 h, elderly 16 h
Contra-indications: Myasthenia gravis, respiratory and hepatic failure, sleep apnea

Dose: Start on 0.25 - 0.5 mg 3 dd, then 0.5 - 3 mg daily in divided doses
Retard tablet: Start 1 mg 1-2 dd, then 0.5 - 3 mg daily in divided doses

NL: 0.25 and 0.5 mg tablets, Retard tablets 0.5, 1 and 2 mg (Xanax)
UK: CD4-1, not NHS
0.25 and 0.5 mg tablets, Xanax

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