ATC: N05BA05
DDD: 20 mg oral
ICD-10: F41, F10
Metabolised to active metabolite N-desmethyldiazepam
Tmax 45 minutes, half-life 2-3 hours
Metabolite half-life: 42 to 96 hours
Contra-indications: Myasthenia gravis, respiratory and hepatic insuffiency, sleep apnea
Dose
Anxiety: 5 mg 3 dd, up to 50 mg 3dd, up to 300 mg in a day
Alcohol withdrawal: 200 to 300 mg in divided doses, IM 20-40 mg every 2 h
UK: Not marketed
NL: Tranxene
5 and 10 mg caps
Film-coated tabs 20 mg MB (can be quartered), and 50 mg
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