Prazepam

ATC: N05BA11
DDD: 30 mg
ICD-10: F41

First pass effect to N-desmethyldiazepam, tmax 6 h
Half -life: 42-100 hours, metabolite
Contra-indications: myasthenia gravis, respiratory and hepatic failure

Dose: 10 - 60 mg, usually 30 mg, for no longer than 8 to 12 weeks, decrease out slowly
Elderly, hepatic, renal and respiratory failure: start at 10-15 mg

NL: 10 mg tablets (Reapam)
UK: Not marketed

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